Louisville's Favorite Boutique MedSpa
Intentional Aesthetics.
Natural Results.
World-class medical aesthetics with southern hospitality. Founded by CRNA Jana Brewer in Louisville's Frankfort Avenue corridor.
What We Offer
Our Services
From injectables to permanent makeup, every treatment is tailored to enhance your natural beauty.
Injectables
Botox, dermal fillers, Sculptra, Kybella, and PDO threads for natural-looking rejuvenation.
Skin Treatments
HydraFacials, chemical peels, microneedling, and laser treatments for radiant skin.
Permanent Makeup
Microblading, lip blushing, and permanent eyeliner for effortless everyday beauty.
Body Contouring
Non-invasive body sculpting treatments to help you look and feel your best.
Facials & Peels
Customized facial treatments and professional peels for every skin type and concern.
Weight Loss
Medically supervised weight management programs tailored to your goals.
Our Story
A Different Kind
of Med Spa
Founded in 2021 by Jana Brewer, CRNA, XO Aesthetic Refinery was born from a simple belief: every person deserves to feel confident in their own skin, and the path to getting there should feel as intentional as the results.
Nestled on Frankfort Avenue in Louisville's Crescent Hill neighborhood, we've grown from Louisville Lush Aesthetics into a full-service boutique med spa where clients come as clients and leave as friends. Our approach combines clinical precision with genuine warmth.
"We're not just about aesthetics; it's about harnessing scientific breakthroughs to uplift the human spirit, to see beauty as a holistic concept."
Meet Our Team
CRNA
Nurse-Led Care
2021
Established
By the Numbers
Trusted by Louisville
CRNA
Nurse-Led
6+
Treatment Types
2021
Founded
Louisville
Frankfort Ave
Our Team
Meet the Experts
A team of skilled professionals dedicated to your aesthetic goals.
Ready to Refine
Your Aesthetic?
Book a consultation and discover the XO difference.
Book Your Consultation